Helicobacter pylori除菌後に増大した胃底腺ポリープに腺癌が発生した１例

南澤 昌郁; 大工原 誠一; 大野 和幸; 倉石 康弘; 伊東 哲宏; 平山 敦大; 長屋 匡信; 太田 浩良; 菅 智明; 田中 榮司

doi:10.11280/gee.64.1550

GASTRIC ADENOCARCINOMA ON THE SURFACE OF A FUNDIC GLAND POLYP ENLARGED AFTER HELICOBACTER PYLORI ERADICATION: A CASE REPORT

Masafumi MINAMISAWA , Seiichi DAIKUHARA, Kazuyuki ONO, Yasuhiro KURAISHI, Akihiro ITO, Atsuhiro HIRAYAMA, Tadanobu NAGAYA, Hiroyoshi OTA, Tomoaki SUGA, Eiji TANAKA

Author information

Masafumi MINAMISAWA Corresponding author
Department of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine.
Seiichi DAIKUHARA
Department of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine.
Kazuyuki ONO
Department of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine.
Yasuhiro KURAISHI
Department of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine.
Akihiro ITO
Department of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine.
Atsuhiro HIRAYAMA
Endoscopic Examination Center, Shinshu University School of Medicine.
Tadanobu NAGAYA
Department of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine.
Hiroyoshi OTA
Department of Clinical Laboratory Sciences, School of Health Sciences, Shinshu University School of Medicine.
Tomoaki SUGA
Endoscopic Examination Center, Shinshu University School of Medicine.
Eiji TANAKA
Department of Internal Medicine, Division of Gastroenterology, Shinshu University School of Medicine.

JOURNAL FREE ACCESS FULL-TEXT HTML

2022 Volume 64 Issue 9 Pages 1550-1556

DOI https://doi.org/10.11280/gee.64.1550

《掲載論文》vol.64 No.9 p.1531

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Abstract

A 69-year-old woman had been taking a proton pump inhibitor (PPI) for reflux esophagitis since 2005 and also succeeded to Helicobacter pylori(H. pylori) eradication in 2015. EGD revealed multiple gastric polyps in 2017, one of them was suspected to be malignant based on biopsy findings. The polyp gradually enlarged with an irregular depression on its surface; therefore, endoscopic mucosal resection was performed for further diagnosis and treatment. Histopathological assessment confirmed adenocarcinoma on the fundic gland polyp (FGP); however, findings suggestive of gastric mucosal atrophy or H. pylori infection were absent. Gastric adenocarcinoma arising from a PPI-related FGP is rare. Thus, when adenocarcinoma on an FGP is suspected, carefully follow-up and endoscopic resection are recommended.

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