ENDOSCOPIC FINDINGS OF GASTROINTESTINAL GRAFT-VERSUS-HOST DISEASE ENTERITIS AND DRUG-INDUCED ENTERITIS

Abstract

Endoscopic findings are important for the diagnosis of various types of enteritis. However, because various conditions have similar endoscopic findings, histological analysis of biopsy specimens is crucial for differentiating among them and understanding their background factors. The characteristic endoscopic findings of various gastrointestinal conditions include edema, low vascular permeability, and mucosal exfoliation in gastrointestinal graft-versus-host disease enteritis; map-like erosions and shallow and round or longitudinal ulcers in non-steroidal anti-inflammatory drug (NSAIDs)-induced enteritis; pseudomembranes in Clostridioides difficile infection; edema, granular mucosa, cracks, and mucosal tears in collagenous colitis; and redness, granular mucosa, edematous mucosa, and reduced translucency in immune-related Adverse Events (irAE) enteritis. Recognizing the characteristic endoscopic findings of each disease can significantly facilitate diagnosis.