2023 Volume 65 Issue 11 Pages 2304-2309
A 74-year-old woman with chronic diarrhea and abdominal pain visited a primary care physician. The patient was suspected ischemic colitis (IC) by colonoscopy. After 3 months, she was referred to our department because the symptoms did not improve. Colonoscopy revealed edematous/granular mucosa with extensive ulcer in the cecum (descending colon), and IC was suspected. However, we diagnosed collagenous colitis (CC) based on medical history of lansoprazole administration and clinical symptoms. The diagnosis of CC was confirmed by biopsy of the longitudinal ulcers of the sigmoid colon. On day 7, her diarrhea became mild after lansoprazole was discontinued, and the ulcer disappeared on endoscopy. Although CC with extensive ulcer is extremely rare, there are cases that require differentiation from IC as endoscopic appearance and should be attended.
