2023 Volume 65 Issue 6 Pages 1123-1127
A 68-year-old man tested positive for fecal immunochemical test during colorectal cancer screening and underwent lower gastrointestinal endoscopy at our hospital. Endoscopic examination revealed a 6-mm-diameter elevation in the ascending colon and a 3-mm-diameter, flat, well-defined lesion in the transverse colon. Endoscopic resection of the two lesions was performed for diagnostic and therapeutic purposes. Pathological examination revealed that both lesions showed spindle-shaped cell proliferation with infiltration of eosinophils and lymphocytes in the intrinsic layer of the colonic mucosa. Immunohistochemical staining showed spindle-shaped cells that were CD34-positive and negative for c-kit, EMA, GLUT-1, S-100, andα-SMA. Therefore, we diagnosed these lesions as inflammatory fibrinoid polyp (IFP). We report a rare case of endoscopically resectable IFP that was microscopic and found in multiple lesions.