2023 Volume 65 Issue 9 Pages 1415-1420
A 70-year-old female underwent an esophagogastroduodenoscopy. On white light imaging, a slightly elevated, granular, yellowish-white lesion was observed in the upper esophagus. Using magnifying narrow-band imaging, we observed yellowish-white circular structures arranged in an orderly fashion with dilated but uniformly shaped blood vessels. Histopathological examination revealed hyperkeratosis of the squamous epithelium and aggregation of foamy histiocytes beneath the epithelium, leading to a diagnosis of verruciform xanthoma. Over a three-year follow-up period, there was no change in the lesions. We report a case of esophageal verruciform xanthoma diagnosed using magnifying narrow-band imaging.