2025 Volume 67 Issue 5 Pages 1060-1068
Background: Recently, the incidence of superficial non-ampullary duodenal epithelial tumors (SNADETs) has been increasing in Japan. The detection rate of SNADETs and associated factors were investigated in Japanese health checkup examinees who underwent EGD.
Methods: The overall detection rate of SNADETs was calculated for 13,138 patients who underwent EGD during a five-year observation period. Moreover, an objective index, the SNADET detection rate (SDR), was defined as the ratio of detected SNADET cases to the number of EGD cases for each endoscopist. The clinical factors associated with the SDR were analyzed and statistically extracted.
Results: The overall detection rate of SNADETs was 0.21% (27/13,138 cases), which was higher than that previously reported in Japan (0.03-0.04%). SDR varied depending on the endoscopist (SDR range; 0.29-5.95‰, median; 1.39‰). Statistical analysis demonstrated that endoscopists with a high SDR detected significantly more SNADETs in the inferior duodenal angulus and horizontal part of the duodenum than other endoscopists.
Conclusion: Thorough duodenal observation, including the inferior duodenal angulus and horizontal part of the duodenum, during upper gastrointestinal screening in health checkups may improve the overall detection rate of SNADETs.
