ENDOSCOPIC OBSERVATION OF THE GASTRIC MUCUS IN VIVO STAIEND WITH AZURE A.TO MUCUS STAINING.

3. APPLICATION OF SECRETIN STIMULATION

Abstract

The authors studied on the application of secretin, which was reported to increase the amount of the mucuscomponents in the gastric juice, to the mucus stainingin vivo of the stomach with azure A.Experimentally, the intensity of the mucus stained in vitro and in vivo was measured by the reflection modechromatoscanner, using rats. Secretin increased the staining intensity of the surface mucus of the stomach in 15 minutes in rats.In healthy young adults, also, the staining intensity of the mucus was increased by the administration of secretin (1.0u/kg) prior to in vivo staining. The poorly stained area adjacent to gastric ulcer scar could be observed more clearly.