Abstract
The patient was a 48-year-old multipara. when she had a hysterectomy for the diag-nosis of uterine myoma in June 1976, the diagnosis of hydatidif orm mole was made by histological examination and anticacer drug was given. In February 1978, she visited our hospital with a complaint of right hypochondralgia. Laboratory data showed a positive test for human chorionic gonadotropin. Radiographic examination revealed metastatic lesions in lungs and liver. An upper gastrointestinal series and endoscopic examination demonstrated a submucosal tumor on the greater curvature of the antrum, which was diagnosed gastric metastasis of the chorioepithelioma by histological examination of biopsied specinen. Methotrexate re-markably decreased the size of gastric metastatic lesion. It is well known that chorioepithelioma metastasizes hematogenously in the early stage. However, only seven cases with metastasis of chorioepithelioma in stomach has been re-ported previously in Japan. In addition, all previous cases were found at gastrectomy or autopsy. As far as we reviewed, our patient is the first case whose diagnosis was made by endoscopic gastric biopsy.
