BLOOD FLOW DISTRIBUTION IN THE HUMAN STOMACH WITH GASTRIC CANCER

Abstract

Angiographic examination has many advantages for the diagnosis of stomach cancers and at the same time can detect the nature and the metastases to the liver or to the neighboring organs. But angiographic findings are not useful in the evaluation of the blood flow in the tumor. So we measured gastric blood flow using endoscopic method with hydrogen electrode and investigated the blood flow distribution in the center, marginal wall of cancer and its surrounding normal mucosa. Results of our examination were as follows, 1) In the advanced gastric cancers, the blood flow in the marginal wall of cancers was increased when compared with that in the normal surrounding mucosa, and the flow in the marginal wall was also higher than that in the center of cancers. 2) The blood flow in the marginal wall of Borrmanns type-1 and type-2 advanced gastric cancers was slightly higher than that of Borrmann's type-3 and type-4 cancers. 3) In the advanced cancers the blood flow in well differentiated adenocarcinomas was slightly higher than that in poorly differenciated adenocarcinomas or signetring cell carcinomas. 4) In the early gastric cancers, the blood flow in the cancerous area was slightly higher than that in the surrounding norman mucosa, and this was especially manifest for type-I and type-IIa early cancers. 5) In the early gastric cancers there were no remarkable differences in the blood flow of well differenciated, poorly differenciated or signet ring cell carcinoma. 6) No particular differences weer found in the blood flow from the viewpoint of patients' age or the location of gastric cancers.