GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
DUBIN-JOHNSON SYNDROME ASSOCIATED WITH FATTY LIVER ; REPORT OF A CASE
Shinichi TOZUKAToshihiko NOUCHITsuneo ABEMichio MARUYAMATsuneo KAWASAKINaohito MINATOYasushi HASUMURAJugoro TAKEUCHI
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1984 Volume 26 Issue 1 Pages 75-78_1

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Abstract
We repored a case of the Dubin-Johnson syndrome associated with fatty liver, whose liver did not show the characteristic features of greenish-black color. A 29-year-old man was admitted because of jaundice. On admission, marked obesity, jaundice and hepatomegaly were present. The serum bilirubin concentration was 2.8 mg/dl, and direct bilirubin was 2.1 mg/dl. An extended bromsulphalein (BSP) test showed a late rise curve. On laparoscopy, the liver was not greenish-black but sparsity of black spots was present and observed on the smooth liver surface. The histological findings showed a remarkable fatty liver without any evidence of inflammation. The liver cells containing brown granules were small in number because of fatty degeneration of the hepatocytes.
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© Japan Gastroenterological Endoscopy Society
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