Abstract
A rare case of colonic Crohn's disease which occurred rapidly and deteriorated during a short period was reported. A twenty-two years old male who had been completely well developed acute watery diarrhea, lower abdominal pain and high fever followed by pronounced hypoproteinemia and weight loss of 10 kg. He was transferred to our hospital for the further evaluation of colonic lesion which was found by barium enema and colonof iberscopic examination done in another hospital. Stool examinations for parasites and pathogenic bacteria were negative. Both barium enema and colonofiberscopic examination revealed typical longitudinal ulcers and cobble stone appearance in the whole large intestine except for the rectum. Granuloma associated with giant cell was demonstrated in the biopsy specimen taken from the colon. No abnomalities were found in the stomach and small intestine. Diagnosis of Crohn's disease with acute onset was strongly suspected from the clinical course as well as X-ray and endoscopic findings of the colon and confirmed by granuloma in the biopsy specimen of the colon.
