Abstract
A case of Crohn's disease of the stomach was reported together with a review of four reported cases of gastroduodenal Crohn's disease in Japan. A twenty-year-old male who had Crohn's disease of the colon scarred by prednisolone complained of persistent vomiting and weight loss for a year. Laboratory studies revealed hypoproteinemia, hypochloremia and low serum iron level. Tuberculin reaction was negative. An upper gastrointestinal tract roentgenological series showed "ram's horn" deformity of antrum with poor distensibility and irregular cobblestone mucosa. Endoscopy showed linear ulcerations and mucosal nodularities, and endoscopic biopsy revealed a granuloma. With the progression of the gastric outlet obstruction, partial gastrectomy with a Billroth II gastrojejunostomy was elected. The microscopic examination of the specimen revealed the typical features of Crohn's desease like transmural inflammation, fissure and epithelioid granuloma with giant cells. At present time, 10 months after surgery, the patient feels well without steroids nor salicylazosulfapyridine and has gained 11 kg.
