GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
GASTRIC SARCOIDOSIS-A LONG-TERM FOLLOW-UP CASE-
Toshiyuki KATOKoji SATOYukifumi SAITOMasayuki NIWAYoshinori IKARASHIKazuei OGOSHI
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1986 Volume 28 Issue 1 Pages 120-126_1

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Abstract

A 43-year-old male patient having an episode of reccurent epigastric pain has been treated with a diagnosis of gastric sarcoidosis and followed-up by gastroscopy for 7 years. Initial examinations were done in March 1978. Multiple ulcer scars with converging folds were noted in the f ornix and body on upper GI series. Gastroscopy showed on irregular, nodular mucosa with converging folds in the f ornix, open ulcers and scars in the body. Biopsy specimens taken from the gastric lesions revealed non-necrotizing granulomatous inflammation with giant cells. Laboratoly findings showed negative Kveim test and normal angiotensin converting enzyme. Chest X ray finding was also normal but biopsy specimens taken from bronchial mucosa and scalenoid lymph nodes showed granulomatous inflammation. After administration of steroid, symptoms subsided and gastric ulcer healed. During the past 7 years, gastroscopy were performed on many occasions. At these examinations, new ulcerations were noted on the lesser curvature of the body. Biopsy specimens from the new ulcer margins also showed granulomatous inflammation. The nodular elevated lesion has not changed during the follow-up period. The patient has had no symptoms after administration of steroid but new ulcer and reccurent ulcers developed.

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