Abstract
Ureterosigmoidostomy has been used as a measns of supravesical urinary diversion for both benign and malignant diseases of the urinary bladder. Attention is drawn to the occurrence of colonic polypoid lesions at the site of ureterosigmoidostomy. Colonic mucosa of 29 cases undergone ureterosigmoidostomy were studied endoscopically, histologically and histochemically. (1) The age range of 29 patients (22 male, 7 female) was 35 to 78 (mean 61) years. (2) Endoscopical examination of the anastomotic site showed depressed type (9 cases, 24%), flat-elevated type(7 cases, 20%) and elevated type (19 cases, 51%). The most of the elevated type were subpedunculated polypoid lesions. (3) Histologically the polypoid lesions were inflammatory granuloma. The surround-ing mucosa of the polypoid lesions was endoscopically essentially normal, but histologically, edema, slightly inflammatory cell infiltration and an increase of Paneth's cells were revealed. (4) Endoscopic biopsies were obtained from the polypoid lesions and the surrounding mucosa at pre and postoperation of ureterosigmoidostomy. Biopsy specimens were stained with high iron diamine-alcian blue pH 2.5 (HID-AB). In preoperation group, the mucin in the goblet cells was a sulphomucin dominant as well as that of normal control. In postoperation group, however, the mucin was a sialomucin dominant.
