RECURRENCE OF DUODENAL ULCERS

-WITH SPECIAL REFERENCE TO SERUM PEPSINOGEN 1-

Abstract

A follow-up study was made for one year or more after complete endoscopical healing of 142 duodenal ulcer patients. The recurrence was found in 47.9% within one year. The endoscopical manifestation (solitaly, kissing or linear) was unable to predict recurrence of the ulcer. Seventy point six persent of the patients had a hyperpepsinogenemia 1 in endoscopically recurrent ulcer group, and 77.0% had a normopepsinogenemia 1 in endoscopically non-recurrent ulcer group, and the difference of serum pepsinogen 1 level was statistically significant between recurrent and non-recurrent ulcer group (p<0.01). It was concluded in this study that determination of the serum pepsinogen 1 level is useful for the prediction of recurrence of duodenal ulcer.