Abstract
In endoscopic injection sclerotherapy (EIS) for esophageal varices, inflow of sclerosing solution into varices can be confirmed by fluororoentgenography. As this procedure is complicated, simpler method is needed. Therefore, we used fluorescein, a fluorescent contrast medium, and confirmed the exact inflow of sclerosing solution without roentgeno-graphy. The subjects consisted of 20 patients with esophageal varices who underwent EIS palliatively or preventively. According to our routine, 50% glucose solution, Aethoxyscler-ol, and human thrombin were directly injected into esophageal varices. In this procedure, 10% fluorescein was added to the 50% glucose solution. During EIS, injected varices changed yellowish green in color. Cardiac varices similary changed in some subjects. When local elevation of varices following color change at the site of injection, extravar-iceal injection was considered at the time the injection volume of sclerosant was dis-continued. This mininal volume of extravariceal injection resulted in a decrease in ulcers after EIS. When color change occurred in varices other than injected varix, demonstrating inflow of the sclerosing agent, varices without color change could be injected serially and effectively. No accidents were encountered in this procedure.
