Abstract
A case of early gastric cancer resembling submucosal tumor was presented and the literature was reviewed. The patient was a 63-year-old female with a chief complaint of epigastric discomfort. Radiografic and endoscopic examinations of the stomach revealed a lesion suggestive of submucosal tumor with central ulceration. After the diagnosis of gastric cancer was confirmed by biopsy, subtotal gastrectomy was performed. Histopath-ological studies revealed localized cancer nests in the ulcerated portion assosiated with submucosal heterotopic gastric glands and marked proliferation of Collagenous fibers in the submucosa. The final histological diagnosis was moderately differentiated adenocar-cinoma with submucosal invasion (Sm). Reports on early gastric cancer presenting as submucosal tumor have been rare. In this case the protrusion was composed of cancer, submucosal heterotopic gastric glands, and the fibrous reaction in the submucosal layer. Collagenous fibers in the submucosa appeared to be the principal component of the protrusion.