Abstract
A 21-year-old female with a chief complaint of epigastric pain was referred to our hospital. A barium meal study revealed multiple ulcers at the gastric angle and antrum. An endoscopic examination demonstrated a variety of findings such as ulcers with white coating, erosions and hemorrhage at the same regions. With these findings, malignant lymphoma was intially suspected. But histologic examination on biopsy specimens did not reveal any findings suggestive of lymphoma or other malignant neoplasms. On laboratory examinations, the serological test for syphilis showed to be gastric syphilis. The abnormal endoscopic findings and titers of serological test for syphilis were remarkably improved 3 months after treament with Ampicillin. Finally, the diagnosis was confirmed by demonstra-tion of Treponema pallidum on biopsy specimens by silver staining technique using Wartin -Starry's method.