Abstract
Eighty three patients (107 cases) undergoing ERCP, endoscopic sphincterotomy (EST), endoscopic variceal sclerotherapy (sclerotherapy) and colonoscopy were intravenously administered f lunitrazepam as the preendoscopic medication agent. The drug was diluted in lOml saline and injected intravenously in volume of 0.025 mg/kg. Sedative effects were shown in all cases and in the state of closing eyes verbal responce was observed 96 cases (90%). Amnesic effects were identified in 28 of 30 cases (93%). The mean recovery time was 186 minutes. Depression of systolic blood pressure, greater than 40% compared to the premedicative pressure were obvserved in 5 cases (4.6%). Transient excitement and eupholia were noted in 4 cases (3.7%). The pain durindg endoscopic examination was remembered in 7 cases (6.5%). The only one patient complained of arm pain. Flunitrazepam is a very useful intravenous sedative agent for endoscopy in addition to its strong amnesic action.
