CHOLANGIOGRAPHIC STUDY BY ERC AFTER INTRAARTERIAL INFUSION CHEMOTHERAPY AND TRANSCATHETER ARTERIAL EMBOLIZATION IN PATIENTS WITH HEPATOCELLULAR CARCINOMA

Osamu HASEBE; Kendo KIYOSAWA; Yoshiaki MATSUDA; Katsuhide SHIMAKURA; Kenji MUKAWA; Taiji AKAMATSU; Yoshiyuki NAKANO; Takeshi SODEYAMA; Seiichi FURUTA; Syouji KAJIKAWA; Naoto HORIGOME

doi:10.11280/gee1973b.34.1569

Osamu HASEBE, Kendo KIYOSAWA, Yoshiaki MATSUDA, Katsuhide SHIMAKURA, Kenji MUKAWA, Taiji AKAMATSU, Yoshiyuki NAKANO, Takeshi SODEYAMA, Seiichi FURUTA, Syouji KAJIKAWA, Naoto HORIGOME

Author information

Osamu HASEBE
The Second Department of Medicine, Shinshu University School of Medicine
Kendo KIYOSAWA
The Second Department of Surgery, Shinshu University School of Medicine
Yoshiaki MATSUDA
The Second Department of Surgery, Shinshu University School of Medicine
Katsuhide SHIMAKURA
The Second Department of Surgery, Shinshu University School of Medicine
Kenji MUKAWA
The Second Department of Surgery, Shinshu University School of Medicine
Taiji AKAMATSU
The Second Department of Surgery, Shinshu University School of Medicine
Yoshiyuki NAKANO
The Second Department of Surgery, Shinshu University School of Medicine
Takeshi SODEYAMA
The Second Department of Surgery, Shinshu University School of Medicine
Seiichi FURUTA
The Second Department of Surgery, Shinshu University School of Medicine
Syouji KAJIKAWA
The Second Department of Surgery, Shinshu University School of Medicine
Naoto HORIGOME
The Second Department of Surgery, Shinshu University School of Medicine

JOURNAL FREE ACCESS

1992 Volume 34 Issue 7 Pages 1569-1579

DOI https://doi.org/10.11280/gee1973b.34.1569

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Abstract

We performed ERC in 10 patients with hepatocellular carcinoma after intraarterial infusion chemotherapy and transcatheter arterial embolization. Extensive and severe bile duct necrosis was recognized in 3 patients. Cholangiographic characteristic was irregular stenosis of the bile duct in hepatic portion to peripheral bile duct and it resembles primary sclerosing cholangitis. These 3 cases complicated gallbladder necrosis and hepatic infarction. In one case bile duct necrosis occurred only after CDDP infusion, and thrombosis of intralobular artery was seen in pathological study. These results indicated that ischemia due to anticancer drug-induced intravasucular thrombosis cause bile duct necrosis.

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