A CASE OF CHRONIC HEPATITIS C MANIFESTED DISAPPEARANCE OF REDDISH MARKINGS ON THE LIVER SURFACE AFTER INTERFERON THERAPY

Nobuyuki SAKAI; Minoru UKIDA; Toshio ITO; Kazuhide YAMAMOTO; Koukichi MIZUTAMARI; Masahito TANIMIZU; Takeshi KAKIO; Haruhiko KOBASHI; Ryuichi MATSUO; Reiko MIYAMOTO; Masayuki MIKAMI; Masaki OMOTO; Sousuke NAKANISHI; Nobuhiko OMORI; Masahiro NAKAGAWA; Toshihiko DOI; Gotaro YAMADA; Takao TSUJI

doi:10.11280/gee1973b.35.365

Nobuyuki SAKAI, Minoru UKIDA, Toshio ITO, Kazuhide YAMAMOTO, Koukichi MIZUTAMARI, Masahito TANIMIZU, Takeshi KAKIO, Haruhiko KOBASHI, Ryuichi MATSUO, Reiko MIYAMOTO, Masayuki MIKAMI, Masaki OMOTO, Sousuke NAKANISHI, Nobuhiko OMORI, Masahiro NAKAGAWA, Toshihiko DOI, Gotaro YAMADA, Takao TSUJI

Author information

Nobuyuki SAKAI
First Department of Internal Medicine, Okayama University Medical School
Minoru UKIDA
First Department of Internal Medicine, Okayama University Medical School
Toshio ITO
First Department of Internal Medicine, Okayama University Medical School
Kazuhide YAMAMOTO
First Department of Internal Medicine, Okayama University Medical School
Koukichi MIZUTAMARI
First Department of Internal Medicine, Okayama University Medical School
Masahito TANIMIZU
First Department of Internal Medicine, Okayama University Medical School
Takeshi KAKIO
First Department of Internal Medicine, Okayama University Medical School
Haruhiko KOBASHI
First Department of Internal Medicine, Okayama University Medical School
Ryuichi MATSUO
First Department of Internal Medicine, Okayama University Medical School
Reiko MIYAMOTO
First Department of Internal Medicine, Okayama University Medical School
Masayuki MIKAMI
First Department of Internal Medicine, Okayama University Medical School
Masaki OMOTO
First Department of Internal Medicine, Okayama University Medical School
Sousuke NAKANISHI
First Department of Internal Medicine, Okayama University Medical School
Nobuhiko OMORI
First Department of Internal Medicine, Okayama University Medical School
Masahiro NAKAGAWA
First Department of Internal Medicine, Okayama University Medical School
Toshihiko DOI
First Department of Internal Medicine, Okayama University Medical School
Gotaro YAMADA
First Department of Internal Medicine, Okayama University Medical School
Takao TSUJI
First Department of Internal Medicine, Okayama University Medical School

JOURNAL FREE ACCESS

1993 Volume 35 Issue 2 Pages 365-371

DOI https://doi.org/10.11280/gee1973b.35.365

Details

Abstract

A 33-year-old man with chronic hepatitis C showed marked changes on the liver surface after interferon therapy. The first peritoneoscopic diagnosis was code number 314, 2 by Shimada's classification, and histologic finding of the specimen taken from the liver revealed chronic aggressive hepatitis 2B with submassive hepatic necrosis. Six million units of alpha-interferon were administered subcutaneously three times a week for 6 months. The second peritoneoscopic diagnosis after a year of the therapy was code number 311, 6, and histologic finding showed liver fibrosis. Disappearance of reddish markings and appearance of white markings were observed on the liver in a patient with complete response by interferon therapy.

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