Abstract
A 18-year-old male was admitted to our hospital because of rectal bleeding. Endo-scopic examination showed a semi-pedunculated polypoid lesion (10 mm) in the rectum. Endoscopic polypectomy was performed by the snare cautery procedure and the his-tological findings showed diffuse infiltration of plasmacytes. Immunostaining (ABC method) demonstrated a monoclonal feature of the intracellular IgG-λ. No evidence of complicating multiple myeloma was observed by examinations including serum M-protein, urinary Bence-Jones protein, Ga-scintigraphy and bone marrow biopsy. From these results, we diagnosed this case as solitary extramedullary plasmacytoma.
We reported the first case of colonic plasmacytoma removed by endoscopic polypectomy and reviewed 25 cases which have been reported in the literature.