GASTROENTEROLOGICAL ENDOSCOPY
Online ISSN : 1884-5738
Print ISSN : 0387-1207
ISSN-L : 0387-1207
A CASE OF LIVER SARCOIDOSIS COMPLICATING CHRONIC TYPE C HEPATITIS
VALUE OF LAPAROSCOPY IN DIAGNOSIS AND CONFIRMATION OF RESPONSE TO STEROID THERAPY
Chizuko YAGIYasuo BATDaisuke TAKAGIShuji KAWAMURAYoshio KAMEDAMeiko NISHIUCHIKei SEOYoshitake SHINJITakashi KOHRO
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1993 Volume 35 Issue 8 Pages 1894-1899_1

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Abstract
A 66-year-old woman was admitted to our hospital for further examination of liver dysfunction. A test for second generation HCV antibody was positive. The image of abdominal ultrasonography and CT scan showed multiple SOLs in the liver. The initial laparoscopy revealed multiple yellow-white flecks and several large yellow-white nodules, 10mm in size on the liver surface. Needle biopsy of the flecks and nodules revealed non-caseating epithelioid cell granuloma containing giant cells and prominent lymphocytic infiltration into the adjacent tissue, compatible with liver sarcoidosis complicating chronic type C hepatitis. Because of these multiple nodules, the patient was treated with pred-nisolone. Three weeks after the steroid therapy, multiple SOLs at abdominal ultrasono-graphy disappeared. The second laparoscopy 2 months after the start of therapy disclosed the decrease of yellow-white flecks and convertion of large nodules into depressed scars. Liver dysfunction due to hepatitis C remained unchanged.
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© Japan Gastroenterological Endoscopy Society
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