1994 Volume 36 Issue 11 Pages 2156-2163
In our institution, preoperative intra-arterial chemotherapy was started for advanced gastric carcinoma from January 1988. We have performed pre- and post-chemotherapeutic endosonographic examination in 38 cases for 3 years and 3 months since January 1990. We evaluated the effectiveness of chemotherapy with endoscopic ultrasonography (EUS) in comparison between pre- and post-chemotherapeutic effects with cross-section of lesions, and compared its results with the study of endoscopic findings and histopathological examination of the resected stomach. In our result, tumor reduction was observed in 8 of 38 cases from EUS images, but endoscopic and histopathological findings were not always so effective. Consequently, it is believed that EUS provides one of the objective indices of cancer chemotherapeutic effects by visualizing the cross-section of tumor. However, we have some problems for the evaluation and cancer chemotherapeutic effects on each case should be judged on the basis of multilateral findings.