A CLINICAL STUDY ON RECURRENCE OF ESOPHAGEAL VARICES AND ADDITIONAL THERAPY AFTER COMBINED METHOD OF CLIPPING AND ENDOSCOPIC INJECTION SCLEROTHERAPY

Abstract

The combined method of endoscopic variceal ligation using clipping apparatus (EVL-c) and endoscopic injection sclerotherapy (EIS) was performed in 51 patients with esophageal varices in our department. Twelve of them were observed for over one year after the initial therapy at regular intervals. Non-recurrence period after EVL-c+EIS method were ranged from 2.5 to 13 months, with an average of 5.8 months. Additional therapies for recurrent varices were performed from 2 to 9 times, and the average interval of additional therapies was 4.2 months. There was no statistically significance among total volume of 1% Aethoxysklerol (AS) used in each additional therapy. Although there was no relationship between the length of non-recurrence period and total volume of 1 %AS used in the initial therapy, the more total volume of 1%AS was used in the first additional therapy, the longer non-recurrence period became statistically. The polypoid lesion made after clipping apparatus was fallen, was found in 18.3% and more frequently as more volume of 1%AS was injected in the initial therapy. Telangiectagia could not grow up across the polypoid lesion. Complications with EVL-c+EIS method decreased significantly. In order to maintain the therapeutic effect for a long time while keeping this merit, the additional therapy was thought to be very important.