A CASE OF CHURG-STRAUSS SYNDROME (ALLERGIC GRANULOMATOUS ANGITIS)WITH MULTIPLE COLONIC ULCERS

Abstract

A 19-year-woman with a 2-year history of bronchial asthma visited our hospital because of epigastric pain and nausea. Esophagagastroduodenoscopy revealed multiple white plaques on the esophageal mucosa. Hematological examination showed leukocytasis and eosinophilia in the peripheral blood. Neurological examination an admission disclosed mononeuritis in bilateral upper extremities. Two weeks later, she had hematochezia of sudden onset, and colonoscopic examination revealed multiple shallow ulcers zn the sigmold and descending colon. One month later, puzpuric lesions appeared on the face and lower extremities. Siapsy specimens of the skin showed necrotizing angitis and extravascular granulations with rnarked eosinophilic infiltration. We diagnosed this case as Churg-Strauss Syndrome on the basis of the clinical and pathological findings. Churg-Strauss syndrome is a very rare disease, but gastrointestinal disorders often affect the prognosis far the patient's life.