Abstract
We report a case of acute hemorrhagic rectal ulcer induced by a NSAID suppositoryin a patient with no serious illness. A 82-year-old man was admitted to our hospitalhecause of apoplexy and senile dementia, and he was treated with daily 25 mg of diclofenacsuppository with a complaint of lower leg pain. After one month, he noticed hematemesisand fresh anal bleeding. Endoscopic examination revealed a giant hemorrhagic ulcer of thegastric angle and exposed vessel on the anterior wall of the rectum aproximatory 5 cmabove from the anal verge. The rectal ulcerous lesion healed by a conservative supportivetherapy. It is supposed that NSAIDs supposittories should be considered as one of thecausative factors of acute hemorrhagic rectal ulcer.
