THREE CASES OF REFLUX ESOPHAGITIS AFTER ERADICATION THERAPY OF Helicobacter pylori

Abstract

Helicobacter pylori (HP) eradication therapy was performed in 117 patients with gastric and/or duodenal ulcer using 20 mg of omeprazol (or 30mg of lannsopurazol), two antibiotics (400 mg of clarithromycin/500 mg of metronidazole or clarithromycin/1g of amoxicilin) and 2g of ecabet sodium (or 150 mg of palaprezinc) . After cure of HP infection and gastric/duodenal ulcer, three patients developed an endoscopically proven reflux esaphagitis gyrate 2.6% . Two were duodenal ulcer patients and the other a gastric ulcer patient, who have been treated previously with H₂ receptor antagonist. Thus, it is necessary to pay attention to development of reflux esophagitis after cure of HP infection.