2007 Volume 49 Issue 12 Pages 2984-2990
****Department of Diagnostic Pathology, Kyoto University Hospital. The 57-year-old male patient visited our hospital for the through examination of increased CA 19-9. He had presented no abdominal symptom or abnormal defecation so far. Colonoscopy showed segmental colitis and two elevated lesions ; type 0-II a at the ascending colon and type 0-Isp at the descending colon. We diagnosed this case as the high grade dysplasia and the colitic cancer associated with ulcerative colitis (remission state of the total colitis), and he underwent a total colectomy. Such a case with colitic cancer at the time of diagnosis of UC is very rare, and so we report it and considered about the high risk marker of the colitic cancer, including gene mutation.