A CASE OF ALLERGIC GRANULOMATOUS ANGIITIS : HISTOLOGICAL FINDINGS WERE OBTAINED BY COLONOSCOPIC BIOPSY

Abstract

A 71-year-old woman with a history of asthma was admitted to our hospital with edema, numbness and muscle weakness of the ambilateral crura. Hematological tests revealed eosinophilia. Colonoscopic examination demonstrated multiple shallow irregular-shaped ulcers in the entire colon. A biopsy specimen of the ulcer showed granulomatous vasculitis with infiltration of eosinophils in the mucosal layer. A diagnosis of allergic granulomatous angiitis was made. After the administration of prednisolone, the eosinophil counts decreased and colonoscopic findings improved. Colonoscopic biopsy may be helpful in the diagnosis of allergic granulomatous angiitis.