Abstracts of Annual Meeting of the Geochemical Society of Japan
Abstracts of Annual Meeting of the Geochemical Society of Japan
Session ID : 2A05
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Host: Abstracts of Annual Meeting of the Geochemical Society of Japan

Involvement of leucine-mevalonate pathway in characteristic isoprenoidal lipid biosynthesis in halophilic archaea
*Noriaki Yamauchi, Ryo Tanoue
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Keywords: leucine, mevalonate, halophilic archaea, isoprenoidal lipid
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Abstract
The biosynthetic mechanism of characteristic isoprenoidal lipid-core in halophilic archaea was investigated. The fate of deuterium from the stereospecifically deuterium-labeled leucine revealed the stereospecific conversion of prochiral hydrogen in leucine to isoprenoidal lipid with high efficiency. It suggest the involvement of isovaleryl-CoA dehydrogenase and leucine-mevalonate pathway through the biosynthesis of isoprenoid in halophilic archaea.
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© 2013 by The Geochemical Society of Japan
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