Genes & Genetic Systems
Online ISSN : 1880-5779
Print ISSN : 1341-7568
ISSN-L : 1341-7568
Short communications
Proposed standard nomenclature for the α– and β-globin gene families
Gabriela AguiletaJoseph P. BielawskiZiheng Yang
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2006 Volume 81 Issue 5 Pages 367-371

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Abstract

The globin family of genes and proteins has been a recurrent object of study for many decades. This interest has generated a vast amount of knowledge. However it has also created an inconsistent and confusing nomenclature, due to the lack of a systematic approach to naming genes and failure to reflect the phylogenetic relationships among genes of the gene family. To alleviate the problems with the existing system, here we propose a standardized nomenclature for the α and β globin family of genes, based on a phylogenetic analysis of vertebrate α and β globins, and following the Guidelines for Human Gene Nomenclature.

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© 2006 by The Genetics Society of Japan
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