Genes & Genetic Systems
Online ISSN : 1880-5779
Print ISSN : 1341-7568
ISSN-L : 1341-7568
Review
Repeat polymorphism analysis for examining genetic variability and the implications for specific traits in dog breeds
Jungwoo EoHeui-Soo Kim
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2013 Volume 88 Issue 5 Pages 273-278

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Abstract
Genetic variations of functional genes in various animal species have been previously examined to understand the relationship between genotypes and phenotypes. Repeat polymorphism can be found in not only coding sequences but also untranslated regions of the protein-coding genes, affecting gene regulation via a variety of mechanisms. In this respect, repeat polymorphisms including microsatellites, variable number of tandem repeats (VNTRs), and short interspersed nuclear elements (SINEs) in relation to functional genes contribute to recognition of genetic or phenotypic variation and individual identification. These elements are biologically valuable markers for studies on association between genetic make-up and behavioral patterns in dog breeds. Hence, to examine the effect of genotype on behavior, studies on this combination are certainly important. Hence, this review could cast light on the functional roles of repeat polymorphisms in dog behavior and breed variation.
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© 2013 by The Genetics Society of Japan
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