抄録
Acriflavine sensitive mutants were isolated from a wild type (acriflavine-resistant) strain of Escherichia coli K-12 and characterized. These mutants form giant colonies on a broth agar medium, unlike another mutant N43 (genotype acrA1) which has been studied. The mutations, both forward and backward, with regard to the colonial size always accompany changes in response to acriflavine, suggesting pleiotropy of gene. The giant colony-forming mutants were not only higher in the rate of exponential growth but also larger in cell size than their parent strains. The mutations fall in the acrA cistron as in mutant N43.
