Abstract
Autosomal, non-maternal effect, sex-specific lethals of Drosophila melanogaster were examined by lactic-aceto-orcein staining and 3H-uridine incorporation autoradiography of larval salivary gland chromosomes. Two classes of lethals were revealed. One class, which affects dosage compensation, in addition to the male-specific lethals, mle, msl-1, and msl-2 reported previously by Belote and Lucchesi (1980a), now includes a male-specific lethal, mle(3)132. The other group which shows normal dosage compensation is a new group and includes a male-specific lethal, C52, and a female-specific lethal, fle(3)100. A possible action of the lethals in the latter group is discussed.
