Global Health & Medicine
Online ISSN : 2434-9194
Print ISSN : 2434-9186
Screening for dental focal infections in febrile patients with hematologic malignancies who received chemotherapy: a retrospective cohort study
Yasuyuki ShimadaYohei KawasakiRyo NasuFumihiko NakamuraYutaka Maruoka
Author information

2020 Volume 2 Issue 4 Pages 255-258


Source of fever in chemotherapy patients is often unknown. Fever can also be fatal. No observational studies have determined the incidence of dental focal infection (DFI)-associated fever, despite oral cavity being a potential source of infection. We report the incidence of fever after chemotherapy in patients with hematological malignancies and their association with DFIs in 441 patients visiting our institution during a 6-year period. Dental treatments, including tooth extraction, were performed, and their oral and hematological profiles were monitored after chemotherapy. Fever was evident in 87 (38.5%) of 226 patients (≥ 38˚C) after the first cycle of chemotherapy. Sepsis due to DFIs (n = 4; 4.6%) was evaluated. Chemotherapy was delayed due to DFI in one case. Fever after chemotherapy should be differentiated from oral infections. Our study emphasizes the significance of DFI in patients with fever after chemotherapy and can help in improving the prognosis of patients.

Information related to the author
© 2020 National Center for Global Health and Medicine
Previous article Next article