Global Health & Medicine
Online ISSN : 2434-9194
Print ISSN : 2434-9186
A novel anticoagulation treatment protocol using unfractionated heparin for coronavirus disease 2019 patients in Japan, 2022
Lubna SatoMasahiro IshikaneNobumasa OkumuraNoriko IwamotoKayoko HayakawaKen IsekiHisao HaraNorio Ohmagari
Author information

2022 Volume 4 Issue 4 Pages 233-236


Hypercoagulability, which can be induced by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays an important role in the pathogenesis of coronavirus disease 2019 (COVID-19). Although anticoagulation therapy is expected to decrease the incidence of thrombosis and mortality in COVID-19 patients, the optimal use of anticoagulation therapy has not been established, especially using unfractionated heparin (UFH). Herein, we suggest a new anticoagulation treatment protocol for the use of UFH in Japanese COVID-19 patients. This protocol considers the safety regarding UFH usage, to lower major bleeding events, and reflects the latest evidence and the current situation regarding anticoagulation therapy in Japan.

Content from these authors
© 2022 National Center for Global Health and Medicine
Previous article Next article