Global Health & Medicine
Online ISSN : 2434-9194
Print ISSN : 2434-9186
Epidemiological trends of traveler's diarrhea in Japan: An analysis of imported infectious disease registry data from 2017–2022
Taketomo MarukiKei YamamotoMasaya YamatoToshinori SaharaMichinori ShiranoNaoya SakamotoRyota HaseKoh ShinoharaYukihiro YoshimuraNatsuko ImakitaFumihiro KodamaYoshihiro YamamotoKyoko YokotaYusuke YoshimiChihiro HasegawaSatoshi KutsunaNorio Ohmagari
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2023 Volume 5 Issue 6 Pages 372-376


Traveler's diarrhea (TD) is a global problem, and identifying the causative organisms of TD is important for adequate treatment. Therefore, this study retrospectively analyzed TD cases in patients who returned to Japan after traveling abroad to determine the causative organisms by travel region. We included patients with a final diagnosis of TD registered in the Japan Registry for Infectious Diseases from Abroad database from September 25, 2017, to September 1, 2022, from 14 medical institutions. A total of 919 patients were analyzed; the causative TD pathogen was identified in 188 cases (20%), of which 154 were caused by diarrheagenic bacteria, the most common being Campylobacter spp. (64%). A 2.2 mg/dL C-reactive protein concentration cutoff value had some predictive ability for bacterial TD (negative predictive value, 89%). Therefore, the C-reactive protein level may help rule out bacterial diarrhea and prevent unnecessary antimicrobial administration when patients cannot provide a stool specimen.

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© 2023 National Center for Global Health and Medicine
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