Abstracts of the General Sessions of the Japanese Society for Dental Materials and Devices
44th General Session of the Japanese Society for Dental Materials and Devices
Session ID : P-31
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Host: The Japanese Association for Dental Materials and Devices

Studies of biological reaction of macrophage-like RAW264 cells against Ti particles
*Masayuki Taira, Kaori Sasaki, Setsuo Saitoh, Yoshima Araki
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Abstract
We evaluated the cellular reaction of macrophage-like RAW264 cells cultured in the medium containing Ti particles with a mean diameter of 10 micrometer. RAW 264 phagocytized Ti particles. The cell viability and NO production of RAW264 cultured in the medium containing Ti particles for two days declined to about 90% those of control RAW264 cells. Such decline appeared to be attributed to phagocytosis-related inflammatory cytokines and oxygen free radicals that reduced the cell proliferation.
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© 2004 by The Japanese Society for Dental Materials and Devices
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