Examining the changes mouse osteoblastic cells on sintered TiO2 surface

Abstract

It was examined the inherent changes in mouse osteoblastic cells (MC3T3-E1 cell) placed on two different sintered surfaces: rutile and anatase TiO2, by ALP staining. Anatase TiO2 materials, when heated to high sintering temperatures, become rutile. Anatase TiO2 specimens sintered at low temperatures, anatase crystal phase remained, did not under do this change and resulted in a negative ALP staining, high temperatures, which turned to rutile phase, change resulted in a positive ALP staining.