2020 年 7 巻 3 号 p. 258-267
Purpose: Postprandial hyperglycemia induces a chain reaction of aldehyde production, thus causing vascular endothelial cell damage which greatly increases the risk of cerebral cardiovascular disease. In this study, we verified the postprandial hyperglycemia improvement effect of a resistance exercise using a rubber band after eating. Methods: 66 men and women with no regular exercise habits were recruited, followed by selecting in the order of high fasting blood glucose, 12 subjects (7 males, 5 females, 55.3 ± 5.2 years old) were analyzed. After ingesting cooked rice (200 g), three types of resistance exercises using a super soft rubber band (large or small size) were performed, and blood glucose and insulin levels were measured. The test was non-cross-over, and every week, control (no exercise), GB10 (large, 10 min, 35 kcal), GS10 (small, 10 min, 35 kcal), GS6 (small, 16 min, 21 kcal) of each group was performed. Results: Compared with the control, GS10 showed significantly lower blood glucose levels at 30 min, while GS6 at 30 and 90 min (p < 0.05). There were no differences between groups in glucose AUC, iAUC, Cmax, Tmax, HOMA-IR. The insulin levels of GB10, GS10, and GS6 were significantly higher than those of the control at 60 min (p < 0.05). The low order of fasting blood glucose, Cmax and the high order of insulin AUC were GS6 group (4th), GS10 group (3rd), GB10 group (2nd), control (1st), and indicating accumulative effect of the exercise. There were no adverse events. Conclusion: Middle-aged people with insufficient physical activity performed resistance exercises with this band for 6 to 10 min after eating, leading to reduced postprandial hyperglycemia and an increase in glucose-responsive insulin secretion. In addition, an accumulation effect was observed, suggesting that glycative stress may be improved by continuing this exercise.