An Autopsy Case of Pulmonary Metastasis of Choriocarcinoma
1973 Volume 13 Issue 4 Pages 325-332
Details
1973 Volume 13 Issue 4 Pages 325-332
A patient, 35 yio female, with pulmonary metastasis of choriocarcinoma occurring 4 years after the simple total hysterectomy for choriocarcinoma is the case.
In spite of some clinical evidence of pulmonary metastasis, no elevation of urinary HCG level was detected. Slight elevation of HCG was observed only 5 months after the recognition of an abnormal shadow on chest X-ray.
Improvement was seen on the administration of MTX and VLB, which was followed by the occurrence of tolerance to the drugs. Upon the trial with VCR, on which very few experience has been reported, a definite response, if not dramatic, was observed. Two months later the patient died. Autopsy revealed the extensive metastases of choriocarcionoma.
Significance of measurement of low titer of HCG and trial with VCR in the case of choriocarcinoma were discussed.
