A Case of Malignant Thymoma Presenting S.V.C. Syndrome Remarkably Responsive to Cisplatin-Prednisolone Combined Chemotherapy

Abstract

A 52-year-old man with malignant thymoma presenting S.V.C. syndrome received cisplatin-prednisolone combined chemotherapy preoperatively. As a result, disappearance of the syndrome and remarkable diminution of the tumor were obtained in a short period of time, making circulatory reconstruction unnecessary and total resection possible. Furthermore, postoperative irradiation (50 Gy) and prophylactic readministration of cisplatin were performed. This multi-disciplinary treatment has resulted in 9 months postoperative survival without signs of reccurrence.