1995 Volume 35 Issue 2 Pages 181-186
Abnormal shadows were seen in the chest X-ray film of a 78-year-old asymptomatic male. Chest plain X-rays revealed an irregular coin lesion in left S3. Under a preoperative diagnosis of adenocarcinoma by transbronchial brush cytology, resection of the left superior lobe involving the intercostal muscle was performed. On the resected specimen, a mucinous carcinoma portion and an atypical carcinoid (or small cell carcinoma) portion were recognized. Grimelius stain and electron microscopy confirmed the presence of neuroendocrine granules in both portions, which led to a diagnosis of mucinous neuroendocrine carcinoma primarily arising from the lung. This extremely uncommon case was discussed with special reference to the relevant literature.
