Asymmetric Dihydroxylation of Olefins Using a Novel Microencapsulated Osmium Catalyst

Abstract

We have already developed a recoverable and reusable osmium-catalyst that can be used in asymmetric dihydroxylation of olefins based on a microencapsulation technique. In the presence of a new osmium catalyst (PEM-MC OsO₄), two-phase asymmetric dihydroxylation has been successfully performed, and complete recover and reuse of the catalyst have been achieved. PEM-MC OsO₄ allows asymmetric dihydroxylation of olefins in water as the sole solvent. Furthermore, we have developed a new type of polymer-supported osmium catalyst based on the cross-linked polystyrene. The catalyst was also effective for asymmetric dihydroxylation of olefins in water as the sole solvent.