ジメチル亜鉛を開始剤とする一級アルキルラジカル発生法の開拓とイミンへの付加反応

抄録

We have developed a new tin-free method for the generation of primary alkyl radicals from iodoalkanes using dimethylzinc-air as an initiator. The addition of the generated primary alkyl radicals to N-tosylimines was accelerated by the action of boron trifluoride-diethyl etherate and copper(II) triflate to give the corresponding adducts in good yields after 2-3 h. Air oxygen was essential for the reaction to proceed, showing involvement of a radical process in the reaction.

fig.1