Although ammonia is a readily available and atom-economical nitrogen source, its introduction into organic molecules with high yields and selectivities has been little investigated. In the course of our investigations to address this issue, we have already reported three-component reactions of aldehydes, ammonia, and allylboronates which provide homoallylic primary amines efficiently. Herein, we report further studies on methods using easy-to-handle aqueous ammonia, stereoselective allylation of hydroxyglycine, 2-aza-Cope rearrangement of allylglycine derivatives, and platinum-catalyzed aminoallylation using allyltins.
