EXPERIMENTAL STUDY ON IMMUNOLOGY OF MURINE LEPROSY

PART 3 ON PREVENTION FUNCTION OF SHWARTZMAN SUBSTANCE AGAINST ONSET OF MURINE LEPROSY

Abstract

The work on Shwartzman substance which prevents the onset of murine leprosy revealed following facts:
1) Emulsion of murine bacilli contained Sh factor.
2) Shwartzman phenomen was recognized in white rats as hyperemia and bleeding in viscera or lymph nodes, not as skin reaction.
3) The substance which contained Sh factor did not prevent the onset of murine leprosy.