Abstract
The following facts are necessary to discern regarding to the differentiation between the leprous perforating ulcer and that of other neural diseases.
The clinical change of the extremeties affected by the perforating ulcer is following: The loss of hair is prominent or a little, anasthesia is observed on the skin of the palm and foot-sole, where the perspiration is surspended, and nerve of the forarm and leg is thickened.
Lepra bacilli were proved in granulation and sequestrum of the perforating ulcer in 1 (5%) of 20 nervous types, and 15 (34.10 %) of 44 noduler types.
There are almost same leprous changes in the histo-pathological view of the granulation of the perforating ulcer in nodular type.
The perforating ulcer is not found in early stage of leprosy, and the disease does not almost take place in any case of beginning leprosy.
