1953 Volume 22 Issue 3 Pages 111-112
It is well known that there are numerous lepra bacilli in the fresh nodule. After the treatment with Promin or other drugs, leprosy bacilli are destroyed and take granular form. Lepra cells are filled and swollen with phosphatid lipoid granules through lysis of the bacilli.
It will be produced some products as the result of metabolism of the leprosy bacilli. These products will enter into the blood stream and cause E. N. L. in the skin, Iridocylitis in eyes, Neuritis in nerves.
The histopathological picture is chiefly composed of foamy lepra-cells, leucocytes, lymphocytes and plasma cells. We can not prove any pyogenic bacteria even when the lesion became abscess.